The Hawaii Gastrointestinal Cancers Summit is a CME-accredited event that brings together leading experts in gastrointestinal malignancies to provide a comprehensive review of current and emerging strategies for managing cancers of the gastrointestinal tract. This summit is designed to enhance participants’ knowledge and competence in applying the latest practice-changing clinical data and expert recommendations to improve patient outcomes. The program will include in-depth discussions and analyses of the latest scientific advancements and key updates in gastrointestinal cancers, including gastroesophageal, hepatobiliary, pancreatic, neuroendocrine, and colorectal cancers. Expert faculty will contextualize the use of various therapeutic agents, exploring how to effectively integrate these treatments into patient care. Additionally, case presentations will be featured to address the management of complex and challenging cases.